Searchable abstracts of presentations at key conferences in endocrinology

ea0029p95 | Adrenal cortex | ICEECE2012

ACTH stimulation improves the sensitivity of aldosterone to rennin ratio (ARR) for detecting inappropriate aldosterone secretion

Ishii M. , Asano M. , Hashimoto Y. , Morita Y. , Isono M. , Hukui M. , Hasegawa G. , Nakamura N.

Background: Aldosterone to renin ratio (ARR) is the gold standard for screening of primary aldosteronism (PA). However, the lower value of ARR cannot rule out the possibility of PA. In this study, we evaluated the change of plasma aldosterone concentration (PAC) in ACTH stimulation among hypertensive patients and explored whether it improved the sensitivity of ARR for detecting PA.Method: Eighty-five patients with hypertension with plasma renin activity ...